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Table 2 Mean cysteamine levels

From: A comparison of immediate release and delayed release cysteamine in 17 patients with nephropathic cystinosis

Time in minutes

Mean Cysteamine level (Cystagon®)

Mean Cysteamine level (Procysbi®)

p-value

0

3.49 ± 1.8

4.04 ± 2.88

0.96

30

34.23 ± 47.22

3.72 ± 2.78

0.001

60

56.95 ± 40.21

12.39 ± 13.16

0.002

90

56.33 ± 30.8

24.81 ± 24.24

0.002

120

47.01 ± 26.53

37.98 ± 30.09

0.43

180

23.5 ± 16.44

50.03 ± 28.46

0.002

240

11.4 ± 6.79

28.9 ± 15.87

0.001

300

8.63 ± 4.38

18.33 ± 12.19

0.003

360

6.53 ± 3.62

11.52 ± 7.08

0.016

540

 

5.77 ± 3.26

 

720

 

3.61 ± 2.23

 
  1. This table demonstrates mean cysteamine levels in µmol/l under a single dose of IR-cysteamine (Cystagon®) and DR-cysteamine (Procysbi®) at different point of times, including standard deviations and p-values