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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Two progressed malignant phyllodes tumors of the breast harbor alterations in genes frequently involved in other advanced cancers

Fig. 2

Medical history of a 29-year woman with a recurrent malignant phyllodes tumor (MPT) of the breast (Patient 2). The young woman presented with a lesion in the right breast on mammogram images. Following excision of the lesion, reconstructive surgery was performed. The mass was identified as a MPT without regional or distant spread. Three months later, PET/CT scans demonstrated a large mass in the axillary region. After surgical excision of the lesion and axillary lymph nodes, a node-negative recurrent tumor of the MPT was diagnosed. Adjuvant radiotherapy of the right breast and axilla was administered. Next-generation sequencing (NGS) was performed for both the primary and recurrent MPT. Follow-up examinations showed no local or distant recurrence to date (April 2021)

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