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Table 3 Characteristics of ASD and ADHD in the child and adolescent population in the TS 2000 and TOSCA studies

From: A comparison of two studies and the prevalence and sex ratio of Neurodevelopmental conditions in Tuberous Sclerosis Complex

 

TS 2000—prevalence

TOSCA—prevalence

Chi squared analysis

Child and adolescent

 Definite ASDa

43% (n = 80)

22% (n = 586)

\({X}^{2}\)(1) = 15.54***

 Probable ASDb

68% (n = 80)

–

\({X}^{2}\)(1) = 72.40***

Child and adolescent

 Definite ADHDc

23% (n = 78)

25% (n = 571)

\({X}^{2}\)(1) = 0.07

 Probable ADHDd

46% (n = 78)

–

\({X}^{2}\)(1) = 13.98***

  1. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001
  2. aADI-R and ADOS-2 positive
  3. bADI-R or ADOS-2 positive
  4. cPervasive and persistent ADHD
  5. dPervasive or persistent ADHD
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172