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Table 2 Male and female prevalence of ASD and ADHD in the TS 2000 and TOSCA studies

From: A comparison of two studies and the prevalence and sex ratio of Neurodevelopmental conditions in Tuberous Sclerosis Complex

 

Female prevalence

Male prevalence

Chi-squared analysis

TOSCA (n = 786)

 ASD

13.5%

28.9%

\({ X}^{2}\)(1) = 27.15***

TS 2000 (n = 80)

 Definite ASDa

40.5%

45.9%

\({X}^{2}\)(1) = 0.07

 Probable ASDb

75.7%

61.9%

\({X}^{2}\)(1) = 1.15

TOSCA (n = 752)

 ADHD

16.7%

28.1%

\({ X}^{2}\)(1) = 13.45***

TS 2000 (n = 78)

 Definite ADHDc

15.5%

33.3%

\({ X}^{2}\)(1) = 2.46

 Probable ADHDd

35.6%

60.6%

\({ X}^{2}\)(1) = 3.85*

  1. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001
  2. aADI-R and ADOS-2 positive
  3. bADI-R or ADOS-2 positive
  4. cPervasive and persistent ADHD
  5. dPervasive or persistent ADHD