Epidemiological investigation of hemophagocytic lymphohistiocytosis in China

Table 2 The age distribution of the etiology of patients (cases)

Underlying disease	≤ 8y	9–18 years	≥ 19 years	χ₁²	χ₂²	P₁	P₂
Genetic	98	19	11	1.941	18.559	0.164	< 0.001^△△△
EBV	363	106	167	1.153	23.069	0.283	< 0.001^△△△
Lymphoma	16	13	161	10.041	50.516	0.002^**	< 0.001^△△△
Other infections	85	10	42	7.163	2.401	0.007^**	0.121
Other tumors	7	4	17	1.541	0.962	0.214	0.327
Rheumatic	27	20	31	13.562	3.054	< 0.001^***	0.081
other	14	5	13	0.308	0.006	0.579	0.940
unknown	135	23	58	4.964	0.001	0.026	0.970

χ₁ is the comparison between ≤ 8 years old and 9 to 18 years old, P₁ is the probability; χ₂ is the comparison between 9 to 18 years old and ≥ 19 years old, P₂ is the probability; P < 0.017 Significantly different (Data from the three groups were compared two by two, corrected P < α/k (α = 0.05, k = 3) was statistically significant)
^**P < 0.01 significantly different
^***P < 0.001 significantly different
△△△P < 0.001 significantly different

ISSN: 1750-1172