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Table 3 Multivariate analysis of risk factors for OS in newly diagnosed adult HLH patients

From: Increased levels of serum interleukin-10 are associated with poor outcome in adult hemophagocytic lymphohistiocytosis patients

Prognostic factor

HR

95% CI

P

Hemoglobin < 8.2 g/dL

1.100

0.612, 1.978

0.750

Platelets < 40 × 109/L

1.589

0.914, 2.764

0.101

LDH ≥ 700 IU/L

0.880

0.458, 1.692

0.702

Albumin < 28 g/L

1.625

0.779, 3.390

0.196

Post-treatment ferritin > 1050 µg/L

3.814

2.042, 7.126

 < 0.001*

IL-10 ≥ 129 pg/mL

4.087

2.064, 8.090

 < 0.001*

  1. HR, hazard ratio; CI, confidence interval
  2. *Indicates statistically significant values