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Fig. 4 | Orphanet Journal of Rare Diseases

Fig. 4

From: Auditory cortex hypoperfusion: a metabolic hallmark in Beta Thalassemia

Fig. 4

Polynomial fitting of the second order between relative left and right auditory cortex perfusion values (rCBF L-AC and rCBF R-AC) and Pure Tone Average (PTA). Circles and lines indicate the subjects and the linear relationship between PTA and rCBF (red for hearing loss in at least one frequency (fHL), blue for hearing loss with abnormal Pure Tone Average (HL)); the curve in black is the second-order polynomial fitting (Robust fit bisquare) and the relative R-square value considering all the subjects together. Three subjects were excluded from this analysis because of outlier values of PTA, secondary to cholesteatoma in 1 and otosclerosis in 2

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