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Table 2 Average annual cost of illness due to Gaucher disease (GD) in China ($, n = 41)

From: Economic burden and health related quality of life of ultra-rare Gaucher disease in China

  Mean annual costs 95% CI Ratio of COI (%)
Low limit Upper limit
Direct healthcare cost 41,816.2 ± 65,745.4 21,064.4 62,568.0 85.74
Outpatient medical treatment 1838.1 ± 3029.4 881.9 2794.4 3.77
Inpatient medical treatment 7451.2 ± 10,392.2 4171.1 10,731.4 15.28
Pharmaceutical treatment 29,907.6 ± 63,861.1 9750.6 50,064.7 61.32
Medical tests 1675.9 ± 3207.2 663.6 2688.2 3.44
Formal care 580.6 ± 817.7 322.5 838.7 1.19
Other cost/expenditures 362.7 ± 654.3 156.2 569.3 0.74
Other cost/expenditures of outpatient 88.1 ± 159.7 37.7 138.5 0.18
Other cost/expenditures of inpatient 274.6 ± 633.0 74.8 474.5 0.56
Direct non-healthcare cost 4974.4 ± 4675.9 3498.5 6450.3 10.20
Accommodation 1245.0 ± 1711.2 704.9 1785.1 2.55
Accommodation of outpatient 440.3 ± 597.8 251.6 629.0 0.90
Accommodation of inpatient 804.7 ± 1562.6 311.5 1297.9 1.65
Transportation 819.9 ± 841.5 554.3 1085.5 1.68
Transportation of outpatient 581.8 ± 685.9 365.3 798.3 1.19
Transportation of inpatient 238.0 ± 376.3 119.3 356.8 0.49
Meals 749.8 ± 874.9 473.7 1026.0 1.54
Meals of outpatient 277.3 ± 356.2 164.8 389.7 0.57
Meals of inpatient 472.6 ± 740.1 239.0 706.2 0.97
Costs for artificial nutrition 1340.0 ± 2796.6 457.3 2222.7 2.75
Other cost/expenditures 819.7 ± 929.0 526.4 1112.9 1.68
Direct cost 46,790.6 ± 65,714.2 26,048.6 67,532.5 95.94
Indirect cost     
Productivity loss to caregiver due to caring 1980.4 ± 1962.8 1360.9 2600.0 4.06
Cost of illness (COI) 48,771.0 ± 65,616.8 28,059.8 69,482.2 100.00
  1. Because of rounding, percentage might not add up to exactly 100%
  2. COI = cost of illness; COI is the annual per-patient in this study
  3. *The medical costs were converted to US Dollar using Purchasing Power Parities (PPP) in the study years (2018) (OECD National Accounts Statistics: PPP https://data.oecd.org/conversion/purchasing-power-parities -ppp.htm#indicator-chart)