Table 4 Impact of possible influencing variables on the change of CSF CHIT1 levels during 14 months
From: Increased chitotriosidase 1 concentration following nusinersen treatment in spinal muscular atrophy
ΔCHIT1 | B (CI95%) | SE B | β | R2 | ΔR2 |
|---|---|---|---|---|---|
Model | 0.255 | 0.197** | |||
Constant | 2.564** (1.046; 4.081) | 0.750 | |||
Patients’ height (cm) | − 0.014* (− 0.028; − 0.000) | 0.007 | − 0.449 | ||
SMN2 copy number | − 0.222 (− 0.694; 0.250) | 0.233 | − 0.166 | ||
Age at start of therapy (year) | 0.006 (− 0.015; 0.027) | 0.010 | 0.110 |