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Fig. 4 | Orphanet Journal of Rare Diseases

Fig. 4

From: Cholbam® and Zellweger spectrum disorders: treatment implementation and management

Fig. 4

Heubi et al. [21]: impact of cholic acid therapy on bile acid levels, liver chemistry, and height and weight. ALT, alanine transaminase, AST, aspartate transaminase. A Urinary bile acids at baseline, worst postbaseline response, and best postbaseline response (total population). B Height and body weight: baseline, worst postbaseline response, and best postbaseline response (total population). Change from baseline over time in C serum alanine aminotransferase and D serum aspartate aminotransferase. In panels A, C, and D, numbers within the bars indicate n values. Reprinted from Heubi and Setchell [21]. This is an open access article distributed under the terms of the Creative Commons CCBY-NC-ND license, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal

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