Table 3 Clinical characteristics of the development cohort

Number of patients

18

16

5

5

14

10

Number of lymphocytes analyzed

872

751

253

249

706

637

Age

60.0 ± 3.8

70.9 ± 2.1

73.0 ± 3.0

65.0 ± 6.2

62.4 ± 2.5

61.2 ± 4.0

Gender(M/F)

6/12

12/4

3/2

4/1

11/3

3/7

Smoking (yes/no)

9/9

10/5 (NR: 1)

2/3

3/2

12/2

4/6

Total cell count (*10⁴/ml)

2.12 ± 0.34

3.33 ± 0.76

2.07 ± 0.20

3.56 ± 0.92

2.51 ± 0.46

2.64 ± 0.33

Lymphocyte count (*10⁵/ml)

7.13 ± 1.07

15.4 ± 4.17

8.15 ± 2.00

13.2 ± 4.08

11.9 ± 3.45

13.8 ± 2.94

Fraction of lymphocyte (%)

34.0 ± 2.67

42.0 ± 3.71

38.3 ± 6.09

37.6 ± 10.4

42.1 ± 3.62

50.8 ± 5.82