Table 2 Discriminating ability of the fractions of lymphocytes with small and round nuclei
Fractions of lymphocytes with | ||||
|---|---|---|---|---|
small area and low radius ratio | small area and increased roundness | short perimeter and low radius ratio | short perimeter and increased roundness | |
Cutoff value | 16.4% | 23.0% | 14.0% | 21.9% |
Development cohort | ||||
Sensitivity | 0.944 | 0.944 | 0.944 | 0.889 |
Specificity | 0.820 | 0.780 | 0.800 | 0.820 |
Accuracy | 0.853 | 0.824 | 0.838 | 0.838 |
Validation cohort | ||||
AUROC (95% CI.) | 0.938 (0.865–1.000) | 0.922 (0.847–0.998) | 0.933 (0.857–1.000) | 0.928 (0.832–1.000) |
Sensitivity | 1.000 | 1.000 | 1.000 | 1.000 |
Specificity | 0.711 | 0.622 | 0.733 | 0.711 |
Accuracy | 0.755 | 0.679 | 0.774 | 0.755 |