Skip to main content
Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Quantitative parameters of lymphocyte nuclear morphology in bronchoalveolar lavage fluid as novel biomarkers for sarcoidosis

Fig. 3

Fractions of lymphocyte with small or round nucleus. a The fractions (%) of lymphocytes with small nuclear areas in sarcoidosis, HP, NSIP, COP, DILD, and CTD-ILD were 66.8ā€‰Ā±ā€‰4.7, 49.6ā€‰Ā±ā€‰5.1, 35.7ā€‰Ā±ā€‰1.4, 51.0ā€‰Ā±ā€‰6.8, 25.4ā€‰Ā±ā€‰5.0, and 35.3ā€‰Ā±ā€‰4.4, respectively. b The fractions (%) of lymphocytes with short nuclear perimeters in sarcoidosis, HP, NSIP, COP, DILD, and CTD-ILD were 53.7ā€‰Ā±ā€‰5.3, 32.1ā€‰Ā±ā€‰4.3, 25.1ā€‰Ā±ā€‰1.4, 28.3ā€‰Ā±ā€‰6.4, 14.0ā€‰Ā±ā€‰3.4, and 20.6ā€‰Ā±ā€‰2.5, respectively. c The fractions (%) of lymphocytes with low nuclear radius ratios in sarcoidosis, HP, NSIP, COP, DILD, and CTD-ILD were 44.4ā€‰Ā±ā€‰2.9, 28.6ā€‰Ā±ā€‰2.6, 33.2ā€‰Ā±ā€‰6.0, 17.8ā€‰Ā±ā€‰2.7, 23.2ā€‰Ā±ā€‰2.7, and 27.6ā€‰Ā±ā€‰3.2, respectively. d The fractions (%) of lymphocytes with increased nuclear roundness in sarcoidosis, HP, NSIP, COP, DILD, and CTD-ILD were 58.4ā€‰Ā±ā€‰3.4, 40.1ā€‰Ā±ā€‰2.8, 46.8ā€‰Ā±ā€‰6.4, 28.3ā€‰Ā±ā€‰2.8, 30.4ā€‰Ā±ā€‰2.9, and 39.9ā€‰Ā±ā€‰4.0, respectively. The horizontal bars represent the mean values. The p value for the Kruskalā€“Wallis test is shown on the upper right corner of each chart. *the p value for the Mannā€“Whitney U test is under a significance level set at Ī±ā€‰=ā€‰0.010 (five comparisons in five groups). HP, hypersensitivity pneumonia; NSIP, nonspecific interstitial pneumonia; COP, cryptogenic organizing pneumonia; DILD, drug-induced interstitial lung disease; CTD-ILD, connective-tissue disease associated interstitial lung disease

Back to article page