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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Quantitative parameters of lymphocyte nuclear morphology in bronchoalveolar lavage fluid as novel biomarkers for sarcoidosis

Fig. 1

Area, perimeter, radius ratio, and roundness of BALF lymphocyte nuclei. a Areas of BALF lymphocyte nuclei in patients with sarcoidosis, HP, NSIP, COP, DILD, and CTD-ILD were 400.97 ± 2.92 μm2, 439.11 ± 3.10 μm2, 464.19 ± 6.24 μm2, 433.61 ± 4.81 μm2, 480.81 ± 3.24 μm2, and 458.61 ± 2.97 μm2, respectively. b Perimeters of BALF lymphocyte nuclei in patients with sarcoidosis, HP, NSIP, COP, DILD, and CTD-ILD were 71.18 ± 0.30 μm, 75.21 ± 0.31 μm, 76.92 ± 0.58 μm, 75.07 ± 0.47 μm, 79.39 ± 0.32 μm, and 76.81 ± 0.28 μm, respectively. c Radius ratios of BALF lymphocyte nuclei in patients with sarcoidosis, HP, NSIP, COP, DILD, and CTD-ILD were 1.50 ± 0.014, 1.61 ± 0.026, 1.53 ± 0.023, 1.64 ± 0.021, 1.69 ± 0.019, and 1.58 ± 0.016, respectively. d Roundness of BALF lymphocyte nuclei in patients with sarcoidosis, HP, NSIP, COP, DILD, and CTD-ILD was 1.026 ± 0.0018, 1.039 ± 0.0023, 1.032 ± 0.0034, 1.045 ± 0.0035, 1.055 ± 0.0027, and 1.035 ± 0.0020, respectively. The error bars represent the standard error of the mean. *p value is under the significance level set at α = 0.010 (five comparisons in six groups). BALF, bronchoalveolar lavage fluid; HP, hypersensitivity pneumonia; NSIP, nonspecific interstitial pneumonia; COP, cryptogenic organizing pneumonia; DILD, drug-induced interstitial lung disease; CTD-ILD, connective-tissue disease associated interstitial lung disease

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