|
Metabolic characteristics
|
Dercum(n = 9)
|
LMS(n = 11)
|
Obese controls(n = 8)
|
p DD versus obese
|
p LMS versus obese
|
p obese versus lean
|
|---|
|
Clinical data
| | | | | | |
|
Sex ratio (M/W)
|
0.5 (3 M/6F)
|
1.75 (7 M/4F)
|
0.5 (4 M/4F)
|
> 0.99
|
> 0.99
|
0.09
|
|
Age (years)
|
30.8 [16–50]
|
31.2 [18–68]
|
46.5 [23–64]
|
0.44
|
0.21
|
> 0.99
|
|
BMI (kg/m2)
|
32 [27–59]
|
31 [25–35]
|
34.1 [31–43]
|
> 0.99
|
> 0.99
|
0.002
|
|
Treated hypertension (%; n/N)
|
22% (2/9)
|
64% (7/11)
|
38%(3/8)
|
> 0.99
|
> 0.99
|
0.27
|
|
Diabetes (%; n/N)
|
33% (3/9)
|
9% (1/11)
|
25% (2/8)
|
> 0.99
|
> 0.99
|
0.75
|
|
Treated dyslipidemia (%; n/N)
|
11% (1/9)
|
45% (5/11)
|
38% (3/8)
|
> 0.99
|
> 0.99
|
0.22
|
|
Paraclinica
| | | | | | |
|
Hemoglobin (g/dL)
|
14.3 [12.5–15.4]
|
14.6 [12–15.4]
|
14.9[12.8–16.6]
|
0.47
|
> 0.99
|
> 0.99
|
|
Platelets (103/mm3)
|
266 [211–310]
|
220 [104–255]
|
242 [221–283]
|
0.8
|
0.51
|
0.09
|
|
Leukocytes (103/mm3)
|
7.8 [5–9.1]
|
5.8 [5.2–9.8]
|
6.9 [5.1–11.3]
|
0.97
|
0.74
|
0.06
|
|
CRP (mg/L)
|
3 [3–18]
|
3 [3–10]
|
6.3 [3–10]
|
> 0.99
|
> 0.99
|
> 0.99
|
|
Leukocyte differential: (/mm3)
| | | | | | |
|
Lymphocytes
|
1939 [1100–2000]
|
1832 [600–2300]
|
2141 [1500–3300]
|
0.71
|
0.46
|
0.97
|
|
Monocytes
|
500 [500–700]
|
400`[400–600]
|
400 [300–700]
|
> 0.99
|
> 0.99
|
> 0.99
|
|
Nuclear neutrophils
|
5200 [2600–10000]
|
3300 [2500–4600]
|
4050 [2600–7100]
|
> 0.99
|
> 0.99
|
0.16
|
|
Eosinophils
|
150 [0–300]
|
100 [0–500]
|
188 [100–400]
|
> 0.99
|
0.35
|
> 0.99
|
|
Basophils
|
52 [30–100]
|
19 [0–37]
|
22 [0–100]
|
0.03
|
0.97
|
0.14
|
|
Lymphocytes subpopulations (n/N)
|
(5/9)
|
(7/11)
|
(8/8)
| | | |
|
CD3+
|
1420 [1105–1904]
|
867 [513–1584]
|
1688[1215–1982]
|
0.94
|
0.02
|
0.84
|
|
CD4+
|
1255 [790–1710]
|
636.5 [328–922]
|
979 [785–1454]
|
0.96
|
0.01
|
0.77
|
|
CD8+
|
479 [454–788]
|
227[140–310]
|
493 [209–992]
|
> 0.99
|
0.02
|
0.89
|
|
B Lymphocytes
|
204.5 [140–760]
|
227 [101–310]
|
199 [152–346]
|
0.73
|
> 0.99
|
> 0.99
|
|
NK Lymphocytes
|
207.5 [40–225]
|
210 [124–300]
|
287 [226–634]
|
0.06
|
0.31
|
> 0.99
|
- The number of patients studied was indicated only when at least one data point was missing: n: number of examinations performed/ N: total number of patients in the group
- *: p < 0.05, **: p < 0.01, ***: p < 0.001, ns: non significant; p > 0.05*: p < 0.05, **: p < 0.01, ***: p < 0.001, ns: non significant
