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Table 4 Main clinical and immunohematological characteristics of Dercum’s disease (DD) and Roch-Leri lipomatosis (LMS) groups compared to an obese control group

From: Metabolic and immunological phenotype of rare lipomatoses: Dercum’s disease and Roch-Leri mesosomatic lipomatosis

Metabolic characteristics Dercum(n = 9) LMS(n = 11) Obese controls(n = 8) p DD versus obese p LMS versus obese p obese versus lean
Clinical data       
Sex ratio (M/W) 0.5 (3 M/6F) 1.75 (7 M/4F) 0.5 (4 M/4F)  > 0.99  > 0.99 0.09
Age (years) 30.8 [16–50] 31.2 [18–68] 46.5 [23–64] 0.44 0.21  > 0.99
BMI (kg/m2) 32 [27–59] 31 [25–35] 34.1 [31–43]  > 0.99  > 0.99 0.002
Treated hypertension (%; n/N) 22% (2/9) 64% (7/11) 38%(3/8)  > 0.99  > 0.99 0.27
Diabetes (%; n/N) 33% (3/9) 9% (1/11) 25% (2/8)  > 0.99  > 0.99 0.75
Treated dyslipidemia (%; n/N) 11% (1/9) 45% (5/11) 38% (3/8)  > 0.99  > 0.99 0.22
Paraclinica       
Hemoglobin (g/dL) 14.3 [12.5–15.4] 14.6 [12–15.4] 14.9[12.8–16.6] 0.47  > 0.99  > 0.99
Platelets (103/mm3) 266 [211–310] 220 [104–255] 242 [221–283] 0.8 0.51 0.09
Leukocytes (103/mm3) 7.8 [5–9.1] 5.8 [5.2–9.8] 6.9 [5.1–11.3] 0.97 0.74 0.06
CRP (mg/L) 3 [3–18] 3 [3–10] 6.3 [3–10]  > 0.99  > 0.99  > 0.99
Leukocyte differential: (/mm3)       
Lymphocytes 1939 [1100–2000] 1832 [600–2300] 2141 [1500–3300] 0.71 0.46 0.97
Monocytes 500 [500–700] 400`[400–600] 400 [300–700]  > 0.99  > 0.99  > 0.99
Nuclear neutrophils 5200 [2600–10000] 3300 [2500–4600] 4050 [2600–7100]  > 0.99  > 0.99 0.16
Eosinophils 150 [0–300] 100 [0–500] 188 [100–400]  > 0.99 0.35  > 0.99
Basophils 52 [30–100] 19 [0–37] 22 [0–100] 0.03 0.97 0.14
Lymphocytes subpopulations (n/N) (5/9) (7/11) (8/8)    
CD3+ 1420 [1105–1904] 867 [513–1584] 1688[1215–1982] 0.94 0.02 0.84
CD4+ 1255 [790–1710] 636.5 [328–922] 979 [785–1454] 0.96 0.01 0.77
CD8+ 479 [454–788] 227[140–310] 493 [209–992]  > 0.99 0.02 0.89
B Lymphocytes 204.5 [140–760] 227 [101–310] 199 [152–346] 0.73  > 0.99  > 0.99
NK Lymphocytes 207.5 [40–225] 210 [124–300] 287 [226–634] 0.06 0.31  > 0.99
  1. The number of patients studied was indicated only when at least one data point was missing: n: number of examinations performed/ N: total number of patients in the group
  2. *: p < 0.05, **: p < 0.01, ***: p < 0.001, ns: non significant; p > 0.05*: p < 0.05, **: p < 0.01, ***: p < 0.001, ns: non significant