|
Clinical data
|
|
Age (years)
|
30.8 [16–50]
|
31.2 [18–68]
|
32.8 [19–65]
|
0.35
|
0.16
|
0.69
|
|
Weight (kg)
|
89 [58–98]
|
100 [55–142]
|
69 [49–83]
|
0.01
|
0.001
|
0.42
|
|
BMI (kg/m2)
|
32.5 [27–59]
|
31 [25–35]
|
22 [17–25]
|
0.0005
|
0.0002
|
0.71
|
|
Systolic Blood Pressure (mmHG)
|
130 [130–160]
|
140 [115–150]
|
115 [103–146]
|
0.013
|
0.001
|
0.42
|
|
Diastolic Blood Pressure (mmHG)
|
78.6 [60–90]
|
79.7 [70–95]
|
72.5 [68–89]
|
0.04
|
0.04
|
0.93
|
|
Metabolic data
|
|
Triglycerides (g/L)
|
1.22 [0.65–9.42]
|
1.37 [0.74–2.63]
|
0.87 [0.56–2.77]
|
0.07
|
0.83
|
0.98
|
|
HDL-c (g/L)
|
0.45 [0.34–0.55]
|
0.48 [0.41–0.82]
|
0.53 [0.38–0.72]
|
0.17
|
> 0.99
|
0.15
|
|
LDL-c (g/L)
|
1.46 [0.83–2.72]
|
1.22 [0.91–1.87]
|
1.16 [0.92–1.4]
|
0.03
|
0.72
|
0.20
|
|
AST (IU/L)
|
27 [18–43]
|
25 [21–81]
|
22 [17–29]
|
0.05
|
0.09
|
> 0.9
|
|
ALT (IU/L)
|
26 [14–75]
|
28,5 [11–78]
|
17 [10–31]
|
0.05
|
0.09
|
0.72
|
|
Gamma-GT (IU/L)
|
83 [58–125]
|
74 [30–139]
|
18.7 [11–28]
|
0.0001
|
0.0001
|
0.54
|
|
Fasting blood glucose (g/L)
|
1 [0.92–1.33]
|
0.98 [0.84–1.32]
|
0.86 [0.77–1.01]
|
0.0028
|
0.057
|
0.27
|
|
Fasting insulin (µIU/L; n/N)
|
8.1 [6.3–14-4] (7/9)
|
7.35 [6.3–35.8](7/11)a
|
4.6 [1.2–9.2] (18/18)
|
0.004
|
0.014
|
0.68
|
|
Fasting C-peptide (ng/mL; n/N)
|
3.2 [2.46–4.33](7/9)
|
2.57 [1.57–5.21](7/11)a
|
1.75 [1–3.7] (18/18)
|
0.016
|
0.04
|
0.84
|
|
HOMA-IR (n/N)
|
2.67 [1.02–4.2] (7/9)
|
1.67 [1.4–11.6](7/11)a
|
1 [0.25–2.18](18/18)
|
0.0008
|
0.02
|
0.62
|
|
Leptin (ng/mL)
|
47.9 [6.7–224]
|
28.5 [13–110.8]
|
5.1 [4.1–16.1]
|
0.003
|
0.0002
|
> 0.9
|
|
Anthropometric data
|
|
Fat mass estimated in DEXA (%; n/N)
|
37.1 [27.9–44.5](6/9)
|
34.3 [31.5–42.8] (8/11)
|
22.9[17.9–34.9] (18/18)
|
0.008
|
0.004
|
> 0.9
|
|
Intra/total abdominal fat ratio (n/N)
|
0.36 [0.20–0.98](8/9)
|
0.31[0.24–0.6] (5/11)
|
0.19[0.10–0.60] (18/18)
|
0.04
|
0.03
|
0.87
|
