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Table 2 Organ manifestations in TSC patients1 (n = 184)

From: Direct and indirect costs and cost-driving factors of Tuberous sclerosis complex in children, adolescents, and caregivers: a multicenter cohort study

 

%

n

Epilepsy

91.8

169

 Recurrent seizures

47.8

88

 Seizure free > 1 year or no seizures

52.2

96

Structural brain disorders

83.2

153

 SEGA2

33.2

61

 Cortical tubers

76.1

140

 Hydrocephalus

3.3

6

Psychiatric disorders

51.1

94

Heart and circulatory system

66.8

123

 Rhabdomyomas

61.4

113

 Hypertension

6.0

11

 Aneurysm Aorta

1.1

2

 Arrhythmia

7.6

14

Kidney and urinary tract

53.3

98

 Chronic kidney dysfunction

1.6

3

 Angiomyolipomas

45.7

84

 Cysts

29.9

55

Skin manifestations

85.9

158

 Hypomelanotic macules

74.5

137

 Angiofibromas

60.3

111

 Shagreen patches

39.1

72

 Forehead plaque

3.3

6

 Ungal/periungal fibromas

1.1

2

Other disorders

29.9

55

 Iris or retinal hamartomas/astrocytomas

19.0

35

 Angiomyolipomas in other organ systems3

3.3

6

 Cysts in other organ systems3

2.7

5

  1. 1Respiratory system manifestations were not reported
  2. 2Subependymal giant cell astrocytoma
  3. 3Hormone system, Thyroid, Gastrointestinal, Liver, Spleen, Pancreas