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Table 2 Organ manifestations in TSC patients1 (n = 184)

From: Direct and indirect costs and cost-driving factors of Tuberous sclerosis complex in children, adolescents, and caregivers: a multicenter cohort study

  % n
Epilepsy 91.8 169
 Recurrent seizures 47.8 88
 Seizure free > 1 year or no seizures 52.2 96
Structural brain disorders 83.2 153
 SEGA2 33.2 61
 Cortical tubers 76.1 140
 Hydrocephalus 3.3 6
Psychiatric disorders 51.1 94
Heart and circulatory system 66.8 123
 Rhabdomyomas 61.4 113
 Hypertension 6.0 11
 Aneurysm Aorta 1.1 2
 Arrhythmia 7.6 14
Kidney and urinary tract 53.3 98
 Chronic kidney dysfunction 1.6 3
 Angiomyolipomas 45.7 84
 Cysts 29.9 55
Skin manifestations 85.9 158
 Hypomelanotic macules 74.5 137
 Angiofibromas 60.3 111
 Shagreen patches 39.1 72
 Forehead plaque 3.3 6
 Ungal/periungal fibromas 1.1 2
Other disorders 29.9 55
 Iris or retinal hamartomas/astrocytomas 19.0 35
 Angiomyolipomas in other organ systems3 3.3 6
 Cysts in other organ systems3 2.7 5
  1. 1Respiratory system manifestations were not reported
  2. 2Subependymal giant cell astrocytoma
  3. 3Hormone system, Thyroid, Gastrointestinal, Liver, Spleen, Pancreas