Table 1 Concepts identified in targeted literature review
Signs/symptoms | Impacts |
|---|---|
Neuropathic pain (acroparesthesia, Fabry crisis pain, and chronic continuous pain in hands and feet) | Physical activities, including exercise and sports |
Gastrointestinal symptoms (abdominal pain, diarrhea, constipation, nausea, and vomiting) | Work and school productivity |
Impaired relationships (social, intimate, and family) | |
Impaired sweating (hypohidrosis and anhidrosis) | |
Impaired emotional functioning, particularly depression and anxiety | |
Angiokeratoma | |
Hearing impairment (hearing loss, tinnitus) | |
General quality of life | |
Heat intolerance | |
Lymphedema | |
Headache | |
Renal complications (proteinuria, need for dialysis and/or transplant) | |
Cardiac complications (chest pain, palpitations, CHF, and MI) | |
Cerebrovascular complications (stroke and TIA) | |
Ophthalmological issues (corneal verticillate and tortuous vessels) | |
Fatigue, tiredness, or excessive sleepiness |