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Table 2 Distribution of height z-scores of treated and untreated MPS II patients at baseline, year 1, and year 2 of follow up as classified in to age groups

From: A review of the clinical outcomes in idursulfase-treated and untreated Filipino patients with mucopolysaccharidosis type II: data from the local lysosomal storage disease registry

 

All (n = 11)

Treated (n = 2)

Untreated (n = 9)

Group 1

Baseline

 Stunted (z < − 2)

%

1

9%

1

50%

0

 Normal (z < − 1 to >  + 2)

%

10

91%

1

50%

9

100%

 Tall (z >  + 3)

%

0

0

0

Year 1

 Stunted (z < − 2)

%

3

27.3%

1

50%

2

22.22%

 Normal (z < − 1 to >  + 2)

%

8

72.7%

1

50%

7

77.8%

 Tall (z >  + 3)

%

0

0

0

Year 2

 Stunted (z < − 2)

%

3

27.3%

1

50%

2

22.22%

 Normal (z < − 1 to >  + 2)

%

8

72.7%

1

50%

7

77.8%

 Tall (z >  + 3)

%

0

0

0

Group 2

Baseline

(n = 16; Treated = 1; Untreated = 15)

 Stunted (z < − 2)

%

11

68.75%

1

10

66.67%

 Normal (z < − 1 to >  + 2)

%

5

31.25%

0

5

33.33%

 Tall (z >  + 3)

%

0

0

0

Year 1

(n = 13; Treated = 1; Untreated = 12)

 Stunted (z < − 2)

%

10

77%

1

9

75%

 Normal (z < − 1 to >  + 2)

%

3

23%

0

3

25%

 Tall (z >  + 3)

%

0

0

0

Year 2

(n = 10; Treated = 0; Untreated = 10)

 Stunted (z < − 2)

%

7

70%

NA

7

70%

 Normal (z < − 1 to >  + 2)

%

3

30%

NA

3

30%

 Tall (z >  + 3)

%

0

NA

0

Group 3

Baseline

(n = 13; Treated = 5; Untreated = 8)

 Stunted (z < − 2)

%

13

100%

5

100%

8

100%

 Normal (z < − 1 to >  + 2)

%

0

0

0

 Tall (z >  + 3)

%

0

0

0

Year 1

(n = 11; Treated = 5; Untreated = 6)

 Stunted (z < − 2)

%

11

100%

5

100%

6

100%

 Normal (z < − 1 to >  + 2)

%

0

0

0

 Tall (z >  + 3)

%

0

0

0

Year 2

(n = 7; Treated = 4; Untreated = 3)

 Stunted (z < − 2)

%

7

100%

4

100%

3

100%

 Normal (z < − 1 to >  + 2)

%

0

0

0

 Tall (z >  + 3)

%

0

0

0

  1. Group 1: aged < 6 years at start of ERT or at time of diagnosis; Group 2: aged 6–10 years at start of ERT or at time of diagnosis; Group 3: aged > 10 years at start of ERT or at time of diagnosis