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Table 2 Descriptive statistics for ferritin levels and nutritional support: natural protein intake (NPI) (g/kg/day), special mixture of precursor-free amino acids (SMAA) intake (g/kg/day), total protein intake, % of protein provided by natural protein intake

From: Severe anemia in patients with Propionic acidemia is associated with branched-chain amino acid imbalance

Patient

1

2

3

4

5

6

7

8

9

10

Measures (N)

N = 10

N = 24

N = 9

N = 4

N = 12

N = 5

N = 9

N = 3

N = 3

N = 7

Natural protein intake (NPI) (g/kg/day)

Mean (sd)

Min; max

0.29 (0.14)

0.11; 0.46

0.55 (0.25)

0.17; 0.89

0.79 (0.29)

0.4; 1.2

0.58 (0.06)

0.5; 0.65

0.96 (0.07)

0.87; 1.1

0.39 (0.01)

0.38; 0.41

0.72 (0.06)

0.6; 0.3

0.24 (0.00)

0.24; 0.24

0.32 (0.09)

0.21; 0.36

0.28 (0.09)

0.16; 0.36

SMAA intake (g/kg/day)

Mean (sd)

Min; max

1.23 (0.23)

0.92; 1.5

1.97 (0.33)

1.61; 2.77

1.58 (0.2)

1.33; 1.93

1.41 (0.2)

1.2; 1.66

2 (0.09)

1.86; 2.15

0.62 (0.02)

0.61; 0.66

2.3 (0.13)

2.1; 2.5

1.7 (0.00)

1.7; 1.7

0.96 (0.09)

0.91; 1.07

1.0 (0.00)

1.0; 1.0

Amount of total protein from natural protein (%)

Mean (sd)

Min; max

19.1 (8.5)

7.2; 28.5

22 (9.5)

7.4; 35

33 (10)

17; 44

29.5 (4.9)

23; 33.3

35.5 (1.8)

30; 36

38.5 (0.00)

38.5; 38.5

24 (1.9)

19; 26

12 (0.00)

12; 12

25 (7)

16.6; 29

21.5 (5.8)

14; 26

Ferritin (ng/ml). NV: 20–250 ng/ml

Mean (sd)

Min; max

429.1 (223.6)

124; 829

873.1 (768.1)

142; 2926

556.2 (657.2)

103; 2085

56 (28.3)

24; 93

24.6 (11.2)

9; 50

34.4 (6.6)

28; 44

76 (39)

25; 139

25 (23)

10; 53

72.8 (27.3)

51; 103

245 (186)

111; 651