Table 1 Relative risks (RR) of lymphoproliferative malignancies in patients with NF1 in the literature
From: Lymphoproliferative malignancies in patients with neurofibromatosis 1
Study | Year | n | Lymphoma RR (95% CI) | Lymphocytic leukemia RR (95% CI) | Studied population |
|---|---|---|---|---|---|
Narod et al. [13] | 1991 | 90 | 5.1 HL 8.0 NHL 3.4 | 2.7 | Children under the age of 15 years |
Stiller et al. [14] | 1994 | 26 | NHL 10.0 (3.3–23.4) | 5.4 (2.8–9.4) | Children under the age of 15 years |
Seminog et al. [7] | 2012 | 8003 | NHL 3.3 (1.7–6.0) | 2.5 (1.1–4.6) | All age groups |
Uusitalo et al. [8] | 2016 | 1404 | 1.19 (0.39–2.78) | All age groups | |