From: Long-term renal outcome in methylmalonic acidemia in adolescents and adults
Median | Min–Max | Standards | |
---|---|---|---|
Measured GFR (mL/min/1.73 m2) | 56.5 | 23–105 | > 90 |
Estimated GFR by Schwartz formula (mL/min/1.73 m2) | 77 | 26–123 | > 90 |
Estimated GFR by CKD-EPI (mL/min/1.73 m2) | 112 | 31–144 | > 90 |
Serum laboratory data | |||
Urea (mmol/L) | 3.8 | 2.4–8.1 | 2.5–8.0 |
Sodium (mmol/L) | 138 | 135–141 | 136–146 |
Potassium (mmol/L) | 3.8 | 2.8–4.7 | 3.5–4.5 |
Chloride (mmol/L) | 105 | 100–108 | 98–107 |
Uric acid (µmol/L) | 421 | 202–703 | 150–350 |
Magnesium (mmol/L) | 0.83 | 0.68–0.96 | 0.85–1.15 |
Alkaline reserve (mmol/L) | 25 | 22.3–30 | 22–29 |
Total calcium (mmol/L) | 2.3 | 2.2–2.6 | 2.25–2.6 |
Ionized calcium (mmol/L) | 1.17 | 1.13–1.24 | 1.15–1.34 |
Phosphorus (mmol/L) | 1.0 | 0.79–1.4 | 0.85–1.5 |
PTH (pg/mL) | 47.2 | 28.9–106.6 | 10–50 |
25OH vitamin D (ng/mL) | 28 | 15–76 | 30–80 |
1–25 OH vitamin D (pg/mL) | 43 | 23–106 | 30–60 |
Urinary parameters | |||
Fractional excretion of sodium (%) | 1.1 | 0.2–7.0 | NA |
Potassium (mmol/L) | 47.5 | 13.4–118 | NA |
Fractional excretion of potassium (%) | 20.8 | 5.7–63.9 | NA |
Calcium (mmol/L) | 0.5 | 0.5–2.77 | < 3.6 |
Calcium (mmol/mmol)** | 0.07 | 0.02–0.28 | < 0.55 |
Fractional excretion of calcium (%) | 1.8 | 0.5–4.1 | NA |
Fractional excretion of urea (%) | 5.1 | 0.04–12.2 | NA |
Fractional excretion of phosphate (%) | 9.6 | 1.5–48.6 | NA |
Fractional excretion of magnesium (%) | 4.9 | 2.0–11.3 | NA |
TmP-GFR (mmol/L)* | 0.9 | 0.5–1.4 | 0.7–1.4 |
Proteinuria (mg/mmol)** | 8.5 | 0–34.6 | < 50 |
Microalbuminuria (mg/mmol)** | 0.8 | 0–15.4 | < 35 |
β2-microglobulinuria (µg/mmol)** | 6.0 | 0–506 | < 35 |