Fig. 3From: Enzyme replacement therapy and hematopoietic stem cell transplant: a new paradigm of treatment in Wolman diseasePatient 3 duodenal biopsies pre (a) and post (b) HCT showing improvement overtime. a The pre HCT biopsy shows extensive replacement of the lamina propria by foamy macrophage with broadening of villi. In comparison, the post HCT biopsy b shows an essentially normal villous structure with only a few foamy macrophages in the lamina propria (both haematoxylin and eosin stained FFPE sections, × 100 original magnification)Back to article page