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Table 10 Definition of normotensive scleroderma renal crisis

From: French recommendations for the management of systemic sclerosis

Normotensive scleroderma renal crisis
Creatinine levels over 50% above baseline
or creatinine ≥ 120% of the upper normal range in the lab
And one of the following five criteria:
At least one of the following 5 criteria:
Proteinuria ≥ 2+ by strip
Hematuria ≥ 2+ by strip or ≥ 10 RBC by field
Thrombopenia < 100,000/mm3
Hemolysis defined by an anemia not linked to another cause with:
(1) Schizocytes or other RBC fragments found on the blood smear
(2) Increase in the reticulocyte level
Renal biopsy showing a typical appearance of scleroderma renal crisis (fibrinous thrombi, fibrinoid necrosis, glomerular collapse, onion bulb proliferation in pre-glomerular arterioles and arch arteries)