Table 10 Definition of normotensive scleroderma renal crisis

Creatinine levels over 50% above baseline

or creatinine ≥ 120% of the upper normal range in the lab

And one of the following five criteria:

At least one of the following 5 criteria:

Proteinuria ≥ 2+ by strip

Hematuria ≥ 2+ by strip or ≥ 10 RBC by field

Thrombopenia < 100,000/mm³

Hemolysis defined by an anemia not linked to another cause with:

(1) Schizocytes or other RBC fragments found on the blood smear

(2) Increase in the reticulocyte level

Renal biopsy showing a typical appearance of scleroderma renal crisis (fibrinous thrombi, fibrinoid necrosis, glomerular collapse, onion bulb proliferation in pre-glomerular arterioles and arch arteries)