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Fig. 6 | Orphanet Journal of Rare Diseases

Fig. 6

From: Prospective study of the natural history of chronic acid sphingomyelinase deficiency in children and adults: eleven years of observation

Fig. 6

Compromised growth during the observation period. Individual height (cm) by age for males (a) and females (b) in the pediatric cohort overlaid on CDC growth chart percentiles indicated by different colors with 95–97, 50–75 and 3–5 percentiles marked. CDC normative growth charts stop at age 18. Since growth in some patients continued to be below normative curves after reaching adulthood, data through age 20 are included. Individual patient data are indicated by circles connected by blue dashed lines

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