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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Validating online approaches for rare disease research using latent class mixture modeling

Fig. 2

Three latent classes of patients with CHH/KS (n = 154). The LCMM analysis identified distinct subgroups based on demographic, clinical and patient-reported outcome data. a Class I (n = 84) was diagnosed significantly later (p = 0.045) and exhibits high SDS, disease consequences and emotional impact scores and low illness coherence (making sense of one’s disease). b Class II (n = 41) exhibited less severe psychosocial outcomes and greater illness coherence (all p < 0.001 vs. Class I). c Class III (n = 29) was diagnosed the earliest and exhibited relatively modest psychosocial impact. Dx diagnosis, SDS self-rating depression scale, IPQR Illness Perception Questionnaire-Revised

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