Skip to main content
Fig. 6 | Orphanet Journal of Rare Diseases

Fig. 6

From: Down regulation of the expression of mitochondrial phosphopantetheinyl-proteins in pantothenate kinase-associated neurodegeneration: pathophysiological consequences and therapeutic perspectives

Fig. 6

Mutant PANK2 induced neurons show iron accumulation. a Tau positive immunostaining and bright-field (BF) of Prussian Blue staining images of control (C) and P1 induced neurons after 500 μM pantothenate treatment during 20 days. Scale bar = 15 μm. b Representative bright-field images at higher magnification of Control (C) and P1 induced neurons after Prussian Blue staining. Scale bar = 15 μm. c Quantification of Prussian Blue staining. Data represent the mean ± SD of three separate experiments. *p < 0.01 between PKAN patients and controls; ap < 0.01 between untreated and treated cells

Back to article page

Orphanet Journal of Rare Diseases

ISSN: 1750-1172