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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Down regulation of the expression of mitochondrial phosphopantetheinyl-proteins in pantothenate kinase-associated neurodegeneration: pathophysiological consequences and therapeutic perspectives

Fig. 3

Effect of pantothenate treatment on PANK2 transcripts. Control (C) and patients P1, P2 and P3 fibroblasts were treated with 500 μM pantothenate for 20 days. PANK2 transcripts were quantified by qPCR as described in Material and Methods. Data represent the mean ± SD of three separate experiments. *p < 0.01 between PKAN patients and controls; ap < 0.01 between untreated and treated fibroblasts. A.U., arbitrary units

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172