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Table 1 Patient demographics

From: The incidence of hydrocephalus among patients with and without spinal muscular atrophy (SMA): Results from a US electronic health records study

Category SMA cases (N = 5354) SMA cases who developed hydrocephalus (N = 42) Non-SMA matched controls (N = 5354) Non-SMA matched controls who developed hydrocephalus (N = 9)
Age at index date (years)
 Mean 45.0 46.9 45.0 59.7
 Median 45 57 45 70
 Min, max 0, 86 0, 86 0, 86 8, 85
 SD 23.65 30.59 23.65 27.99
Age (years) at index date categories (n, %)
 0 to < 1 95 (1.8) 2 (4.8) 95 (1.8) 0 (0.0)
 1 to < 2 114 (2.1) 3 (7.1) 114 (2.1) 0 (0.0)
 2 to < 13 442 (8.3) 5 (12) 442 (8.3) 1 (11.0)
 13 to ≤ 20 326 (6.1) 3 (7.1) 326 (6.1) 1 (11.0)
 21 to ≤ 30 436 (8.1) 2 (4.8) 436 (8.1) 0 (0.0)
 31 to ≤ 40 926 (17.0) 0 (0.0) 926 (17.0) 0 (0.0)
 41 to ≤ 50 653 (12.0) 1 (2.4) 653 (12.0) 1 (11.0)
 > 50 2362 (44.0) 26 (62.0) 2362 (44.0) 6 (67.0)
Sex (n, %)
 Female 2521 (47.0) 18 (43.0) 2521 (47.0) 3 (33.0)
 Male 2833 (53.0) 24 (57.0) 2833 (53.0) 6 (67.0)
Time in database (months)
 Mean 90.6 96.5 90.6 136.4
 Median 93 107.5 93 159
 SD 46.65 54.66 46.65 42.69
  1. SD standard deviation, SMA spinal muscular atrophy