Table 1 Patient demographics
Category | SMA cases (N = 5354) | SMA cases who developed hydrocephalus (N = 42) | Non-SMA matched controls (N = 5354) | Non-SMA matched controls who developed hydrocephalus (N = 9) |
|---|---|---|---|---|
Age at index date (years) | ||||
 Mean | 45.0 | 46.9 | 45.0 | 59.7 |
 Median | 45 | 57 | 45 | 70 |
 Min, max | 0, 86 | 0, 86 | 0, 86 | 8, 85 |
 SD | 23.65 | 30.59 | 23.65 | 27.99 |
Age (years) at index date categories (n, %) | ||||
 0 to < 1 | 95 (1.8) | 2 (4.8) | 95 (1.8) | 0 (0.0) |
 1 to < 2 | 114 (2.1) | 3 (7.1) | 114 (2.1) | 0 (0.0) |
 2 to < 13 | 442 (8.3) | 5 (12) | 442 (8.3) | 1 (11.0) |
 13 to ≤ 20 | 326 (6.1) | 3 (7.1) | 326 (6.1) | 1 (11.0) |
 21 to ≤ 30 | 436 (8.1) | 2 (4.8) | 436 (8.1) | 0 (0.0) |
 31 to ≤ 40 | 926 (17.0) | 0 (0.0) | 926 (17.0) | 0 (0.0) |
 41 to ≤ 50 | 653 (12.0) | 1 (2.4) | 653 (12.0) | 1 (11.0) |
 > 50 | 2362 (44.0) | 26 (62.0) | 2362 (44.0) | 6 (67.0) |
Sex (n, %) | ||||
 Female | 2521 (47.0) | 18 (43.0) | 2521 (47.0) | 3 (33.0) |
 Male | 2833 (53.0) | 24 (57.0) | 2833 (53.0) | 6 (67.0) |
Time in database (months) | ||||
 Mean | 90.6 | 96.5 | 90.6 | 136.4 |
 Median | 93 | 107.5 | 93 | 159 |
 SD | 46.65 | 54.66 | 46.65 | 42.69 |