Table 1 Motor impairment
Case number | Type of impairment | Movement disorders | Disease | Pathophysiology | Transmission | Risk for offspring |
|---|---|---|---|---|---|---|
Bilateral upper and lower limbs | ||||||
1 | Tetraparesis | No | Type 2 spinal muscular atrophy | Genetic | Autosomal recessive | Low |
2 | Tetraparesis | Yes | Type 2 spinal muscular atrophy | Genetic | Autosomal recessive | Low |
3 | Tetraparesis | Yes | Mitochondrial disorder | Genetic | Mitochondrial | Uncertain |
4 | Tetraparesis | Yes | Charcot Marie Tooth disease | Genetic | Autosomal recessive | Low |
5 | Tetraparesis | No | Autosomal dominant Myopathy | Genetic | Autosomal dominant | High |
6 | Tetraparesis | Yes | Cervical Hemangioma, C2-C3 | Stroke | Not applicable | N/A |
7 | Bone/joints disorders | No | Juvenile chronic arthritis | Inflammatory | Not applicable | N/A |
8 | Bone/joints disorders | No | Ehlers-Danlos Syndrome | Genetic | Autosomal dominant | High |
9 | Bone/joints disorders | No | Ehlers-Danlos Syndrome | Genetic | Autosomal dominant | High |
10 | Ectrodactyly | No | Ectrodactyly of left upper limb, agenesis of right lower limb and left upper limb | Genetic | Possibly autosomal dominant | Uncertain |
Unilateral | ||||||
11 | Congenital Hemiplegia | Yes | Cerebral palsy | Birth asphyxia | Not applicable | N/A |
12 | Congenital Hemiplegia | Yes | Brain malformation | Malformation | Not applicable | N/A |
13 | Hemiparesis | Yes | Left hemiparesis | Stroke | Not applicable | N/A |
14 | Upper limb paresis | No | Brachial plexus birth injury | Birth injury | Not applicable | N/A |
15 | Upper limb paralysis | Yes | Brachial plexus birth injury | Birth injury | Not applicable | N/A |
16 | Amputation | No | Congenital agenesis of a forearm | Malformation | Not applicable | N/A |
17 | Amputation | No | Traumatic amputation of an arm | Trauma | Not applicable | N/A |
Bilateral lower limbs | ||||||
18 | Paraparesis | Yes | Friedreich’s ataxia | Genetic | Autosomal recessive | Low |
19 | Paraparesis | Yes | Spinocerebellar ataxia | Genetic | Autosomal dominant | High |
20 | Paraparesis | No | Autoimmune myopathy | inflammatory | Not applicable | Low |
21 | Brown-Sequard syndrome | No | Spinal astrocytoma | Tumor | Not applicable | Low |
Movement disorder | ||||||
22 | Distal tremor | yes | Tetrahydrobiopterin deficiency | Genetic | Autosomal recessive | Low |