| Range of use |
---|---|
Monitoring | Â |
 Bedside glucometer and blood ketones | Initial work up |
 | Fever, vomiting or diarrhea; at symptoms/ morning fasting values/ frequent daily |
 Continuous glucose monitoring* | Initial work up; for months or years in more severe, pathological KH |
Prevention | Â |
 Dietary |  |
  Complex carbohydrates, protein | Before sleep only; for every meal |
  Meal interval | Dependent on age, severity and frequency of KH |
  Uncooked corn starch | ½–1 (− 2) g/kg, 1–4 × daily |
  Long-release corn starch | Severe, frequent KH |
  Continuous gastrostomy tube feeding | Severe, frequent KH. Night feeding with maltose 1/2–1 g/kg/h; other tube feeding products |
Acute treatment | Â |
 Dietary |  |
  Sugar-rich drinks and food | KH attacks without compromised swallowing. Add complex carbohydrates, eventual protein |
  Buccal carbohydrate gel application | KH attacks with compromised swallowing. 1/2–1 tube, eventually repeated |
 Medication |  |
  I.m. glucagon | Severe KH attacks with unconsciousness. 30–40 mcg/kg, maximal 1 mg. Only if proven efficient and safe at specialist center |
  I.v. glucose or dextrose | Severe KH attack. Ensure PG > 3.9 mmol/L (70 mg/dL). Continue until blood ketones < 0.5 mmol/L |