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Table 2 Predictors of obstructive sleep apnea (OSA) in adults with achondroplasia

From: Obstructive sleep apnea in Norwegian adults with achondroplasia: a population-based study

Variables

OSA (n = 29)

No OSA (n = 20)

Difference

OR (95% CI)

P value

Age > 40 years, %

66

25

41

5.7 (1.6 to 20.3)

0.007

Male gender, %

66

40

26

2.9 (0.9 to 9.3)

0.08

Current smoking, %

7

15

− 8

0.4 (0.1 to 2.8)

0.37

History of adenoidectomy, %

48

45

3

1.1 (0.4 to 3.6)

0.82

History of tonsillectomy, %

41

25

16

2.1 (0.6 to 7.4)

0.24

Berlin Questionnaire (BQ)

 Total BQ score ≥ 2 (high risk), %

86

45

41

7.6 (1.9 to 30.2)

0.004

BQ category 1 (snoring)

 Snoring, %

90

80

10

2.2 (0.4 to 11.0)

0.35

 Loud snoring, %

52

15

37

6.1 (1.5 to 25.3)

0.01

 Frequent snoring, %

76

55

21

2.6 (0.8 to 8.7)

0.13

 Snoring bothering other, %

69

55

14

1.8 (0.6 to 5.9)

0.56

BQ category 2 (sleep)

 Observed breathing stops, %

38

5

33

11.6 (1.4 to 99.3)

0.03

 Unrested sleep, %

66

25

41

5.7 (1.6 to 20.3)

0.007

 Excessive daytime sleepiness, %

72

40

32

3.9 (1.2 to 13.2)

0.03

 Fallen asleep while driving, %

24

10

14

2.9 (0.5 to 15.5)

0.22

BQ Category 3

 Hypertension, %a

48

15

33

5.3 (1.3 to 22.0)

0.02

 Body mass index > 30 kg/m2, %

83

50

33

4.8 (1.3 to 17.7)

0.02

  1. a Hypertension was defined as systolic blood pressure ≥ 140 mm Hg, diastolic blood pressure ≥ 90 mm Hg, or antihypertensive drug treatment