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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Phenotypic and biochemical characteristics and molecular basis in 36 Chinese patients with androgen receptor variants

Fig. 3

The transcriptional activities of WT and mutant AR were investigated using the androgen response element (ARE) promoter. The relative luminescence activity was expressed as a ratio of firefly to Renilla luciferase. a WT and all of the novel mutant AR in LNCaP cells. b WT AR, p.L295P, and p.A588P (as positive control) in 293T cells cultured with variant concentrations of DHT. The error bars represent the standard error. *versus WT P < 0.05; # versus Vector P > 0.05

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