From: Homocystinuria patient and caregiver survey: experiences of diagnosis and patient satisfaction
tHcy (µmol/l) before treatment median (range) [n] | tHcy (µmol/l) at survey median (range) [n] | Statistical significance of difference [pairwise comparisons n] t-values | |
---|---|---|---|
All CBS-deficient patients | 257 (50–640) [44] | 50 (6–310) [61] | P < 0.001 [37] |
10.804 | |||
Pyridoxine nonresponsive | 200 (50–640) [20] | 52 (6–310) [34] | P < 0.001 [15] |
6.837 | |||
Partially pyridoxine responsive | 300 (99–412) [7] | 26 (13–120) [8] | P = 0.001 [7] |
5.976 | |||
Pyridoxine responsive | 257 (110–600) [12] | 59 (11–180) [14] | P < 0.001 [10] |
6.166 | |||
RMD patients | 145 (56–482) [11] | 42 (7–95) [14] | P = 0.006 [11] |
3.433 |