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Table 2 Association between symptoms and epidemiological, clinical and laboratory parameters

From: Neuropsychiatric, cognitive and sexual impairment in mastocytosis patients

 

Depression

Irritability

Neurological symptoms

Cognitive symptoms

Sexual symptoms

Median age

RR (95% CI)

1.2539

(0.8511–1.8475)

0.9307 (0.6903–1.2549)

0.9179

(0.7107–1.1855)

1.1670 (0.8886–1.5327)

1.2591

(0.6741–2.3516)

Frequency of male

RR (95% CI)

0.6774

(0.4508–1.0177)

1.2212

(0.9079–1.6427)

0.8206

(0.6265–1.0748)

1.0521

(0.8031–1.3783)

1.1754

(0.6308–2.1905)

Median diagnostic delay

RR (95% CI)

1.0833

(0.7339–1.5989)

0.9307

(0.6903–1.2549)

1.0940

(0.8456–1.4153)

0.9805 (0.7484–1.2845)

0.9375

(0.5028–1.7480)

Frequency of cutaneous lesions

RR (95% CI)

1.1761

(0.7263–1.9045)

1.0762

(0.7259–1.5955)

1.2107

(0.9047–1.6203)

1.2483 (0.9257–1.6834)

0.9060 (0.3587–2.2883)

Mastocytosis form

RR (95% CI)

1.3578

(0.7589–2.4293)

0.8290

(0.5963–1.1525)

0.9983

(0.7203–1.3836)

0.9809

(0.6987–1.3770)

1.2000

(0.5126–2.8092)

Serum tryptase level

RR (95% CI)

1.3102

(0.8051–2.1322)

1.0190

(0.7295–1.4233)

1.0989

(0.8198–1.4730)

1.1585

(0.8453–1.5878)

0.7814 (0.4136–1.4761)

Bone marrow tryptase level

RR (95% CI)

0.9863

(0.6554–1.4843)

1.0470

(0.7427–1.4759)

1.0628

(0.7973–1.4165)

1.1596

(0.8355–1.6094)

0.7429

(0.3926–1.4058)

KIT mutation status in BM

RR (95% CI)

1.1780

(0.7063–1.9650)

0.9278

(0.6591–1.3060)

0.9968

(0.7378–1.3467

1.0833

(0.7641–1.5358)

0.7704

(0.3856–1.5392)

KIT mutation frequency in skin

RR (95% CI)

0.9267

(0.6020–1.4265)

0.8741

(0.6377–1.1982)

0.9135

(0.6940–1.2023)

0.9687

(0.7170–1.3086)

1.1560

(0.5473–2.4418)