Fig. 1From: RDmap: a map for exploring rare diseasesRare disease maps and clusters (http://RDmap.nbscn.org). The locations reflect the distance among diseases, and the size of the points reflect the prevalence of rare diseases. a Rare disease map and clusters based on phenotype. The top affected systems were listed beside the cluster legends. b Rare disease map and clusters based on gene. More detail about the disease clusters and their relationships were available in the supplemental materialsBack to article page