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Table 2 Comparison of the variables: demographic, anthropometric, lipid status biomarkers, selenium, glutathione peroxidase activity, malondialdehyde, C-reactive protein of A-T patients and controls

From: Selenium levels and glutathione peroxidase activity in patients with ataxia-telangiectasia: association with oxidative stress and lipid status biomarkers

  Variables A-T patients
(n = 22)
Controls
(n = 18)
P-value
Age Years 12.2 (8.5–20.9) 15.8 (9.8–22.8) 0.615a
Gender Male 16 (72.7%) 13 (72.2%) 0.972b
Prepubertal Yes 6 (27.3%) 3 (16.7%) 0.506b
Body mass index (kg/m2) Underweight 9 (40.9%) 2 (11.1%) 0.146b
  Normal 11 (50.0%) 14 (77.8%)  
  Overweight 2 (9.1%) 2 (11.1%)  
Waist circumference cm 60.0 (53.0–64.0) 68.8 (61.0–79.0) 0.004a
Lean body mass kg 24.8 (20.2–29.8) 41.8 (31.0–50.4) 0.001a
Dyslipidemia Yes 14 (63.6%) 11 (78.6%) 0.467b
Lipid profile High CT 13 (59.1%) 4 (28.6%) 0.097b
  High LDL-c 12 (54.4%) 1 (7.1%) 0.005b
  Low HDL-c 4 (18.2%) 6 (42.8%) 0.140b
  High triglycerides 5 (22.7%) 1 (7.1%) 0.370b
  High non-HDL-c 13 (59.1%) 2 (14.3%) 0.014b
Glycemia Elevate
(> 100 mg/dL)
1 (4.5%) 1 (7.1%) 0.633b
HOMA-IR Elevate
(> 3.16)
6 (27.3%) 2 (14.3%) 0.441b
Selenium Adequate
(> 46 μg/L)
13 (59.1%) 11 (78.6%) 0.292b
Glutathione peroxidase Adequate
(> 4171 U/L)
20 (90.9%) 11 (78.6%) 0.357b
Malondialdehyde High
(≥ 3.46 nmol/mL)
16 (72.7%) 5 (35.7%) 0.041b
C-reactive protein High
(> 3 mg/L)
8 (36.4%) 1 (7.1%) 0.062b
  1. Laboratory variables in control group (N = 14)
  2. Significance level of: aMann-Whitney test, Median (IQ25-75). bChi-square test, N (%)
  3. CT, total cholesterol; LDL-c, low density lipoprotein cholesterol; HDL-c, high density lipoprotein cholesterol; NHDL-c, Non-HDL-c; HOMA-IR, homeostasis model assessment of insulin resistance