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Table 2 Univariate log-rank analysis and Cox multivariate analysis of prognostic factors

From: Survival outcomes of surgery in patients with pulmonary large-cell neuroendocrine carcinoma: a retrospective single-institution analysis and literature review

Risk factor

Univariate log-rank analysis (p)

Multivariate analysis

p

HR (95.0% CI)

Age

0.563

  

Sex (median as cut-off)

0.180

  

Smoking history

0.326

  

Duration (median as cut-off)

0.297

  

Surgical approach (PLT versus VATS)

0.004

0.017

0.407 (0.195–0.851)

Surgical scope (sublobar resection versus lobectomy and combined lobectomy)

0.933

  

Tumour location (peripheral type versus central type)

0.942

  

Pathological type (pure versus mixed)

0.471

  

T stage

0.000

  

N stage

0.002

0.034

1.689 (1.042–2.740)

M stage

0.000

0.001

6.712 (2.229–20.211)

Tumour size (median as cut-off)

0.004

0.278

1.637 (0.672–3.983)

TNM stage

0.000

  

Complication (yes versus no)

0.411

  

AT (all)

0.586

  

AT (stage I)

0.054

  

Neoadjuvant therapy

0.037

0.416

0.605 (0.181–2.028)

  1. PLT posterolateral thoracotomy, VATS video-assisted thoracic surgery, HR hazard ratio, CI confidence interval, AT adjuvant therapy, p < 0.05 indicated that there was significant difference