From: Predictors of cervical myelopathy and hydrocephalus in young children with achondroplasia
Characteristics and parametersa | Yes | No | p value |
---|---|---|---|
N | 13 | 52 | |
Sex | |||
Male | 8 (62) | 28 (54) | 0.85 |
Female | 5 (38) | 24 (46) | |
Age (months) | 11.7 ± 6.1 | 14.6 ± 9.3 | 0.29 |
Follow up period (months) | 31.0 ± 22.3 | 41.8 ± 23.8 | 0.15 |
FM AP (mm) | 6.06 ± 1.66 | 9.10 ± 2.22 | < 0.001 |
Cord constriction ratio | 0.37 ± 0.19 | 0.16 ± 0.12 | < 0.001 |
Anterior indentation | |||
0 | 0 (0) | 24 (46) | < 0.001 |
1 | 3 (23) | 21 (40) | |
2 | 10 (77) | 7 (14) | |
Posterior indentation | |||
0 | 0 (0) | 38 (73) | < 0.001 |
1 | 7 (54) | 8 (15) | |
2 | 6 (46) | 6 (12) | |
Indentation index | |||
0 | 0 (0) | 22 (42) | < 0.001 |
1 | 0 (0) | 15 (29) | |
2 | 3 (23) | 8 (15) | |
3 | 4 (31) | 4 (8) | |
4 | 6 (46) | 3 (6) | |
Frontal horn width (mm) | 43.94 ± 11.04 | 40.61 ± 7.88 | 0.22 |
BPD (mm) | 141.17 ± 7.46 | 136.40 ± 8.34 | 0.06 |
Evans ratio | 0.31 ± 0.07 | 0.30 ± 0.06 | 0.51 |
Periventricular HSI | 22.09 ± 20.33 | 11.46 ± 11.92 | 0.02 |
FMD | |||
Yes | 12 (92) | 9 (17) | |
No | 1 (8) | 43 (83) | |
VP shunt | |||
Yes | 0 (0) | 1 (2) | |
No | 13 (100) | 51 (98) | |
Later event | |||
Yes | 0 (0) | 2 (4) | 1.00 |
No | 13 (100) | 50 (96) |