LHON patients (n = 34) | Asymptomatic LHON mutation carriers (n = 37) | General population | |
---|---|---|---|
Self-reported excessive alcohol consumption before onset | |||
(27/34 with data: 21 M/6F) | 8 (30%) | N/A | 14% |
M | 7 (33%) | N/A | M 16% |
F | 1 (17%) | N/A | F 13% |
Self-reported excessive alcohol consumption at study baseline | |||
(64/71 with data) | 7 (26%) | 2 (6%) | 14% |
M | 5 (24%) | 0 (0%) | M 16% |
F | 2 (33%) | 2 (7%) | F 13% |
AUDIT questionnaire, n (%) | |||
Excessive alcohol consumption at study baseline (66/71 with data:32 Pat./34 Asymp.) | 6 (19%) | 4 (12%) | |
Daily alcohol consumption at study baseline, g/day (68/71 with data: 33 Pat./35 Asymp.) | |||
Mean (± SD) | 12.8 (± 15.8) | 6.4 (± 11.1) | |
Range | 0–60 | 0–54 | |
Days of alcohol consumption at study baseline, n (%) (68/71 with data: 33 Pat./35 Asymp.) | |||
Daily | 3 (9.1%) | 1 (2.9%) | |
Weekly | 12 (36.4%) | 10 (28.6%) | |
Seldom | 11 (33.3%) | 19 (54.3%) | |
Non-drinker | 7 (21.2%) | 5 (14.3%) |