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Table 3 Information on self-reported alcohol consumption in our cohort of LHON mutation carriers, at study baseline

From: Smoking and alcohol, health-related quality of life and psychiatric comorbidities in Leber’s Hereditary Optic Neuropathy mutation carriers: a prospective cohort study

 

LHON patients (n = 34)

Asymptomatic LHON mutation carriers (n = 37)

General population

Self-reported excessive alcohol consumption before onset

   

(27/34 with data: 21 M/6F)

8 (30%)

N/A

14%

M

7 (33%)

N/A

M 16%

F

1 (17%)

N/A

F 13%

Self-reported excessive alcohol consumption at study baseline

   

(64/71 with data)

7 (26%)

2 (6%)

14%

M

5 (24%)

0 (0%)

M 16%

F

2 (33%)

2 (7%)

F 13%

AUDIT questionnaire, n (%)

   

Excessive alcohol consumption at study baseline (66/71 with data:32 Pat./34 Asymp.)

6 (19%)

4 (12%)

 

Daily alcohol consumption at study baseline, g/day (68/71 with data: 33 Pat./35 Asymp.)

   

Mean (± SD)

12.8 (± 15.8)

6.4 (± 11.1)

 

Range

0–60

0–54

 

Days of alcohol consumption at study baseline, n (%) (68/71 with data: 33 Pat./35 Asymp.)

   

Daily

3 (9.1%)

1 (2.9%)

 

Weekly

12 (36.4%)

10 (28.6%)

 

Seldom

11 (33.3%)

19 (54.3%)

 

Non-drinker

7 (21.2%)

5 (14.3%)

 
  1. Asymp., asymptomatic mutation carriers; AUDIT, Alcohol Use Disorders Identification Test; Pat., patients; SD, standard deviation