LHON patients at baseline (n = 34) | LHON patients before onset (n = 34) | Asymptomatic LHON mutation carriers (n = 37) | General population | |
---|---|---|---|---|
Smoking status, n (%) | ||||
Ever-smokers | 26 (76%) | 23 (68%) | 15 (41%) | |
M | 22/28 (79%) | 19/28 (68%) | 5/7 (71%) | |
F | 4/6 (67%) | 4/6 (67%) | 10/30 (33%) | |
Current smokers | 16 (42%) | 20 (59%) | 12 (32%) | 25% |
M | 14/28 (50%) | 17/28 (61%) | 5/7 (71%) | 30% |
F | 2/6 (33%) | 3/6 (50%) | 7/30 (23%) | 20% |
Ex-smokers | 10 (29%) | 3 (9%) | 3 (8%) | |
M | 7/28 (25%) | 2/28 (7%) | 0/7 (0%) | |
F | 3/6 (50%) | 1/6 (12%) | 3/30 (10%) | |
Never smokers | 8 (24%) | 11 (32%) | 22 (59%) | |
M | 6/28 (21%) | 9/28 (32%) | 2/7 (29%) | |
F | 2/6 (33%) | 2/6 (33%) | 20/30 (67%) | |
Pack-years, for ever-smokers | ||||
Mean (± SD) | 14.1 (± 13.0) | 21.1 (± 14.5) | ||
Range | 0–42 | 0.1–102 | ||
FTND, for current smokers Nicotine dependence: | ||||
Very high | 2 (15%) | 0 (0%) | ||
High | 1 (8%) | 4 (36%) | ||
Moderate | 2 (15%) | 2 (18%) | ||
Low | 8 (62%) | 5 (45%) |