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Table 1 Demographic and clinical characteristics of patients (N = 242)

From: Clinical characteristics and burden of illness in patients with hereditary angioedema: findings from a multinational patient survey

Parameter Value
Country, n (%)
 France 58 (24.0)
 United Kingdom 57 (23.6)
 Spain 39 (16.1)
 Canada 32 (13.2)
 Australia 28 (11.6)
 Switzerland 8 (3.3)
 Germany 7 (2.9)
 Austria 13 (5.4)
Age, years
 Mean (SD) 43.8 (14.7)
 Range 18–92
Sex, n (%)
 Female 163 (67.4)
 Male 78 (32.2)
 Not indicated 1 (0.4)
HAE type, n (%)
 Type 1 198 (81.8)
 Type 2 44 (18.2)
Mean (SD) age at onset of first HAE symptoms, years 11.5 (8.9)
Mean (SD) age at HAE diagnosis, years 20.8 (13.2)
Mean (SD) delay in diagnosis,a years 9.3 (11.0)
Family history of HAE, n (%)
 Yes 192 (79.3)
 No 45 (18.6)
 Not sure 5 (2.1)
Comorbidities,b n (%)
 Anxiety 63 (26.0)
 Gastrointestinal disorder 43 (17.8)
 Depression 41 (16.9)
 High cholesterol 33 (13.6)
 Hypertension 31 (12.8)
  1. HAE hereditary angioedema
  2. aDelay in diagnosis was calculated as the difference between age at diagnosis and age at onset of first HAE symptoms
  3. bComorbidities reported by ≥ 10% of patients are listed; multiple comorbidities could be reported by the same patient