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Table 1 Demographic and clinical characteristics of patients (N = 242)

From: Clinical characteristics and burden of illness in patients with hereditary angioedema: findings from a multinational patient survey

Parameter

Value

Country, n (%)

 France

58 (24.0)

 United Kingdom

57 (23.6)

 Spain

39 (16.1)

 Canada

32 (13.2)

 Australia

28 (11.6)

 Switzerland

8 (3.3)

 Germany

7 (2.9)

 Austria

13 (5.4)

Age, years

 Mean (SD)

43.8 (14.7)

 Range

18–92

Sex, n (%)

 Female

163 (67.4)

 Male

78 (32.2)

 Not indicated

1 (0.4)

HAE type, n (%)

 Type 1

198 (81.8)

 Type 2

44 (18.2)

Mean (SD) age at onset of first HAE symptoms, years

11.5 (8.9)

Mean (SD) age at HAE diagnosis, years

20.8 (13.2)

Mean (SD) delay in diagnosis,a years

9.3 (11.0)

Family history of HAE, n (%)

 Yes

192 (79.3)

 No

45 (18.6)

 Not sure

5 (2.1)

Comorbidities,b n (%)

 Anxiety

63 (26.0)

 Gastrointestinal disorder

43 (17.8)

 Depression

41 (16.9)

 High cholesterol

33 (13.6)

 Hypertension

31 (12.8)

  1. HAE hereditary angioedema
  2. aDelay in diagnosis was calculated as the difference between age at diagnosis and age at onset of first HAE symptoms
  3. bComorbidities reported by ≥ 10% of patients are listed; multiple comorbidities could be reported by the same patient