Skip to main content

Table 2 Comparison of selected parameters

From: Quantitative assessment of left ventricular longitudinal function and myocardial deformation in Duchenne muscular dystrophy patients

 

Group A (LGE + , EF < 50%) n = 8

Group B (LGE + , EF ≥ 50%) n = 13

Group C (LGE-, EF ≥ 50%) n = 30

Controls n = 18

p

Age (years)

20.6 ± 6.1

15.1 ± 4.8

13.0 ± 5.8*

17.5 ± 2.9

8.10–4

Weight (kg)

68.0 ± 19.9

52.6 ± 23.4*

42.1 ± 15.8*

68.1 ± 10.5

6.10–6

Height (cm)

166 ± 12

152 ± 19*

143 ± 18*

177 ± 18

1.10–9

BMI (kg/m2)

24.4 ± 5.9

22.4 ± 7.6

19.9 ± 4.1

21.8 ± 2.2

0.09

Dyspnoea (n (%))

3 (37.5%)*

3 (23.1%)

1 (3.5%)

0 (0%)

7.10–3

Hypertension (n (%))

3 (37.5%)*

0 (0%)

0 (0%)

0 (0%)

3.10–6

Diabetes (n (%))

0 (0%)

0 (0%)

0 (0%)

1 (5.6%)

0.42

Corticosteroids (n (%))

1 (12.5%)

6 (46.2%)*

15 (50.0%)*

0 (0%)

8.10–4

ACE-inhibitors (n (%))

5 (62.5%)*

8 (61.5%)*

5 (17.9%)

0 (0%)

1.10–4

ARBs (n (%))

2 (25.0%)

0 (0%)

0 (0%)

0 (0%)

1.10–3

β-blockers (n (%))

6 (75.0%)*

1 (7.7%)

1 (3.6%)

0 (0%)

1.10–7

Diuretics (n (%))

3 (37.5%)*

0 (0%)

0 (0%)

0 (0%)

4.10–6

LV EF (%)

37.9 ± 9.9*

61.2 ± 7.1

64.9 ± 6.8

66.3 ± 7.2

1.10–13

LVMi (g/m2)

59.2 ± 12.9

41.8 ± 7.7*

33.5 ± 7.6*

53.6 ± 13.0

3.10–11

LV EDVi (ml/m2)

88.5 ± 29.6*

47.9 ± 8.5*

52.4 ± 13.0*

64.8 ± 11.6

8.10–9

LV ESVi (ml/m2)

55.9 ± 23.9*

18.7 ± 5.12

19.1 ± 7.2

21.6 ± 4.4

7.10–14

LV SVi (ml/m2)

32.6 ± 9.5*

29.1 ± 5.4*

32.8 ± 8.2*

43.3 ± 10.4

1.10–5

  1. Continuous variables are expressed as the mean ± standard deviation; categorical as total count (percentage)
  2. Variables marked in bold have their ANOVA/χ2 test p value < 0.05
  3. *denotes a significant difference compared with the control group (Dunnet post hoc test or a series of 3 Fisher exact tests with Bonferroni correction)
  4. BMI, body mass index (kg/m2); ACE, angiotensin converting enzyme; ARB, angiotensin receptor blockers; LGE + , positive late gadolinium enhancement; LGE–, negative late gadolinium enhancement; LV, left ventricle; EF, ejection fraction; LVMi, left ventricular mass index; EDVi, end-diastolic volume index; ESVi, end-systolic volume index; SVi, stroke volume index