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Table 2 Sex-, age- and period-specific estimates of prevalence and incidence of Huntington disease (HD) in Navarre, for the period 1991–2017

From: Validation of diagnostic codes and epidemiologic trends of Huntington disease: a population-based study in Navarre, Spain

  Number of HD cases Prevalence Incidence
Total Symptomatic Asymptomatic (n)a Total prevalent cases Point prevalence rate per 100,000 (95% CI) Total incident cases Annual incidence rate per 100,000 (95% CI)
Total 80 61 19 65   63 0.40 (0.31, 0.50)
Sex        
Men 38 (47%) 26 12 (4) 15 (47%) b 4.68 (2.31, 7.05)b 29 (46%) 0.37 (0.25, 0.52)
Women 42 (53%) 35 7 17 (53%) b 5.20 (2.73, 7.67)b 34 (54%) 0.43 (0.30, 0.59)
Age (years)        
 ≤ 20 4 1 3 (1) 0b 0b 1 0.03 (0, 0.16)
21–40 22 8 14 (2) 4b 2.64 (0.05, 5.22)b 10 0.19 (0.10, 0.35)
41–60 28 26 2 (1) 10b 5.11 (1.94, 8.27)b 26 0.63 (0.42, 0.91)
 > 60 26 26 0 18b 11.53 (6.20, 16.85)b 26 0.78 (0.52, 1.12)
Period        
1991–1999 26 23 3 (2) 31c 5.70 (3.69, 7.71)c 22 0.46 (0.30, 0.69)
2000–2008 28 21 7 (1) 32d 5.07 (3.31, 6.83)d 21 0.39 (0.25, 0.59)
2009–2017 24 15 9 (1) 32b 4.94 (3.23, 6.65)b 20 0.35 (0.22, 0.53)
  1. aNumber of HD presymptomatic cases that became symptomatic throughout the study period
  2. Point prevalence dates: b31/12/2017, c31/12/1999, d31/12/2008