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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Diagnostic and severity scores for Cockayne syndrome

Fig. 3

Optimal ROC curve for the clinical-radiological diagnostic score showing the maximal area under the curve (AUC) obtained for the score defined in Table 2 Optimal sensitivity and specificity on this curve are 96.2% and 96.8% respectively (a), corresponding to a threshold of 15.5 for the clinical-radiological diagnostic score (b). Solid lines draw the thresholds of 14 and 16 that were chosen to distinguish low/moderate/high likelihood for CS diagnosis based on positive predictive value (not shown)

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