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Table 1 Characteristics of the clinical and pulmonary findings in 71 NF1 patients

From: Structural alteration of lung parenchyma in patients with NF1: a phenotyping study using multidetector computed tomography (MDCT)

Characteristics All NF1 patients
n = 71
Female gender 40 (56)
Age (years ± SD) 33 ± 14
Current smokers 17 (24)
MPNST 30 (42)
Reticulations 18 (25)
GGO 7 (10)
Consolidation 6 (8)
Emphysema 22 (31)
 Centrilobular 5 (7)
 Paraseptal 21 (30)
 Panlobular 0 (0)
Honey combing 0 (0)
Tree-in-bud sign 0 (0)
Nodules 23 (32)
≤ 10 18 (25)
> 10 5 (7)
Max. diameter (mm ± SD) 5 ± 2
Cysts 25 (35)
≤ 10 18 (25)
> 10 7 (10)
Max. diameter (mm ± SD) 8 ± 3
UL 14 (20)
ML 2 (3)
LL 9 (13)
Left 11 (15)
Right 14 (20)
Thickened interlobular septa 10 (14)
Pleural effusion 3 (4)
Pericardial effusion 0 (0)
Pulmonary metastasis 6 (8)
  1. Data are presented as absolute numbers and frequencies (%) or as mean values ± standard deviation (SD)
  2. MPNST malignant peripheral nerve sheath tumor, GGO ground glass opacity, UL upper lobe, ML middle lobe, LL lower lobe