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Table 3 Construct validity

From: Fatigability in spinal muscular atrophy: validity and reliability of endurance shuttle tests

 ESNHPTESBBTESWT
Discriminative validitySMA – HC - DCSMA - HCSMA - HC
Time to limitation
(Mdn (s))
SMA (N = 55): 937 (48–1200)
HC P1 (N = 15): 600
HC P2 (N = 9): 1200
DC (N = 15): 1200 (967–1200)
SMA (N = 37): 245 (50–1200)
HC P1 (N = 15): 600
HC P2 (N = 5): 1200
SMA (N = 15): 861 (218–1200)
HC P1 (N = 12): 600
HC P2 (N = 8): 1200
Drop-out (%)SMA: 54.5%
HC: 0%
DC: 6.7%
SMA type 2: 73.3%
SMA type 3a: 63.6%
SMA type 3b: 7.1%
SMA: 70.3%
HC: 5%
SMA type 2: 100%
SMA type 3a: 80%
SMA type 3b-4: 44%
SMA: 73.3%
HC: 0%
Convergent validitySMASMASMA
Muscle strength (N)No decreaseSA: −5.5 (2.1), p = .013KF: - 8.9, p = .011
Perceived fatigue (0–10)G: + 1.1 (0.2), p = .000
UA: + 2.6 (0.3), p = .000
LA: + 2.8 (0.4), p = .000
H: + 2.4 (0.4), p = .000
UA: + 2.6 (0.4), p = .000)
LA: + 2.1 (0.4), p = .000
H: + 1.0 (0.3), p = .000
G: +  3.7 (0.77), p = .000
UL: +  4.0 (.92), p = .001
Motor adaptation (Yes)No drop-out: 26%
Drop-out: 96%
No drop-out: 33%
Drop-out: 96%
No drop-out: 75%
Drop-out: 100%
  1. ESWT Endurance Shuttle Walk Test, ESBBT Endurance Shuttle Box and Block Test, ESNHPT Endurance Shuttle Nine Hole Peg Test, HC Healthy Controls, DC Disease Controls, P1 protocol 600 s, P2 protocol 1200 s, KF Knee Flexion, SA Shoulder Abduction, G General, UL Upper Limb, UA Upper Arm, LA Lower Arm, H Hand