Experienced complaints, activity limitations and loss of motor capacities in patients with pure hereditary spastic paraplegia: a web-based survey in the Netherlands

Table 3 Multivariate forward logistic regression analyses

Dependent variable: ‘faller’ (self-report of at least two falls a year) (n = 109)
Cofactor	Level of cofactor	n	OR (95% CI)	p-value
Duration of spasticity symptoms	Reference: 1–5 years	21
	5–10 years	21	39.070 (5.405–282.410)	< 0.001
	10–15 years	16	7.789 (1.419–42.757)	0.018
	> 15 years	51	18.025 (3.813–85.220)	< 0.001
Comorbidity	Reference: No	101
Comorbidity	Yes	8	0.162 (0.052–0.509)	0.002
Walking aids indoors	Reference: No wheelchair	87
Walking aids indoors	Wheelchair	22	0.130 (0.029–0.577)	0.007
Rise from floor	Reference: Yes, with ease	12
	Yes, with difficulty	59	17.897 2.759–116.108)	0.002
	No	38	17.934 (2.333–137.878)	0.006
Overall explained variance R² = 0.450
Dependent variable: ‘walker without aids’ (self-report of walking distance without crutch or walker > 500 m) (n = 82)
Cofactor	Level of cofactor	n	OR (95% CI)	p-value
Age	19–84	82	0.944 (0.899–0.994)	0.030
Gait problems	0–10	82	0.604 (0.400–0.911)	0.016
Standing (10 min)	Reference: Yes, with ease	40
Standing (10 min)	Yes, with difficulty	42	0.286 (0.085–0.970)	0.045
Open heavy door	Reference: Yes, with ease	41
Open heavy door	Yes, with difficulty	41	0.165 (0.049–0.564)	0.004
Overall explained variance R² = 0.583

ISSN: 1750-1172