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Table 3 Gender differences in HHT severity

From: Gender differences in hereditary hemorrhagic telangiectasia severity

 

Female

(n = 142)

Male

(n = 100)

P value

Follow-up, months (mean ± SD)

41.9 ± 25.8

40.4 ± 25.3

0.647

ESS

 ESS at baseline (mean ± SD)

3.47 ± 2.19

3.65 ± 2.12

0.536

 ESS during follow-up (mean ± SD)

2.21 ± 1.76

2.52 ± 1.71

0.242

 ESS ≥ 4

61 (42.9%)

37 (37%)

0.379

 ESS ≥ 7

9 (6.3%)

8 (8%)

0.604

Simple Clinical Scoring Index

3.38 ± 1.20

2.03 ± 1.24

< 0.001

 Low

36 (25.3%)

61 (61%)

< 0.001

 Intermediate

90 (63.4%)

31 (31%)

< 0.001

 High

7 (4.9%)

0

0.043

HHT-score

2.31 ± 1.06

2.09 ± 0.88

0.083

 Mild

88 (62%)

69 (69%)

0.259

 Moderate

47 (33.1%)

29 (29%)

0.532

 Severe

7 (4.9%)

1 (1%)

0.245

Invasive treatment

 Pulmonary embolization

34 (23.9%)

16 (16%)

0.126

 Brain embolization

2 (1.4%)

0

0.470

 Liver transplantation

2 (1.4%)

0

0.513

 Young surgery

3 (2.1%)

0

0.270

 Anyone of the above

40 (28.2%)

16 (16%)

0.027

Adverse outcomes

 Hemoglobin < 8 g/dL or RBC transfusion

49 (34.5%)

33 (33%)

0.578

 RBC transfusion

37 (26.1%)

27 (27%)

0.870

 ED visit

40 (28.2%)

48 (48%)

0.002

 Hospital admission

27 (19%)

26 (26%)

0.196

 Mortality

4 (2.8%)

4 (4%)

0.721

 Anyone of the above

70 (49.3%)

53 (53%)

0.570

  1. Abbreviations: EES Epistaxis Severity Score, RBC red blood cell, ED emergency department