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Table 2 Baseline characteristics

From: Treatment of patients with hereditary angioedema with the c.988A>G (p.Lys330Glu) variant in the plasminogen gene

CharacteristicTreated patients with HAE-PLG
N = 59*
Sex, n (%)
 Male17 (28.8)
 Female42 (71.2)
Age, year53.7 ± 17.1
Mean disease duration, year21.4 ± 15.3
Laboratory parameters
 C1-INH activity (%) (RR 70–130)99.4 ± 17.3
 C1-INH protein (mg/dL) (RR 15.4–33.8)24.8 ± 5.6
 C4 (mg/dL) (RR 16.4–31.3)24.0 ± 8.2
 Plasminogen activity (%)91 ± 17.4**
  1. C1-INH C1 inhibitor, HAE hereditary angioedema, HAE-PLG HAE with the c.988A > G (p.K330E) variant in the PLG gene; N number of patients, n number of patients in the specified category, RR reference range, ± standard deviation
  2. *Patients who had received treatment for acute attacks and/or long-term prophylaxis
  3. **in 34 patients only; control group see text